What this episode is about
Confused about hormone replacement therapy? You're not alone. Let's separate fact from fiction with menopause expert Jill Chmielewski and discover what your doctor might not be telling you about hormones.
In this episode
- Understanding Why Hormones Matter More Than We Think
- The Truth About Hormone Decline in Perimenopause
- Debunking the Women's Health Initiative Study Myths
Moments from this episode
Word for word from the recording. Tap a time to hear it.
Forgetting how good you could feel
“I find some women will say, I didn't even realize how bad I felt until I started the HRT. And I'm like, wow, I forgot how good I could feel.”
They are body hormones
“Estrogen, progesterone and testosterone have always traditionally been seen as sex hormones, but they're actually body hormones.”
“Every cell in the body has what we call receptors for hormones. They're like little mini satellite dishes that receive hormone signals.”
Jill Chmielewskiat 6:50
Hear this momentFeel more pleasure, 10 minutes a day.
10 Days of Pleasure is free. One 10-minute turn-on in your inbox each day. Each one comes with the expert from my podcast who explains why it works.
Day 1 lands in your inbox in a minute. My letter comes after the 10 days, and you can unsubscribe any time.
Show notes
For years, mixed messages about hormone replacement therapy (HRT) have left midlife women confused and unsure about their choices. Between the conflicting headlines and outdated medical advice, it's no wonder so many of us feel lost when considering hormone therapy.
That's why I invited registered nurse, menopause educator and women's health expert Jill Chmielewski to share her expertise and help separate fact from fiction.
Read the full show notesShow less
Understanding Why Hormones Matter More Than We Think
Many of us think of estrogen as simply the "sex hormone" - responsible for periods, pregnancy, and maybe hot flashes during menopause. But as Jill explains, estrogen's role in your body is far more extensive and profound:
"We have hormone receptors on our brain, our bones, our skin, our vagina, our urinary tract, our heart, our digestive tract... Every single cell of the body is going to be impacted when those hormones start to decline."
This widespread presence of hormone receptors explains why estrogen decline affects so many aspects of your health:
- Brain Function: Memory, mood, and cognitive clarity
- Cardiovascular System: Blood vessel health and heart function
- Bone Health: Density and fracture risk
- Vision: Macular degeneration risk
- Oral Health: Gum tissue and dental health
- Skin: Collagen production and elasticity
- Metabolic Health: Energy and weight regulation
This is why reducing estrogen to just "sex hormones" misses the bigger picture. As Jill emphasizes, "They really should be called whole body hormones." Understanding this helps explain why menopause symptoms can feel so all-encompassing - and why supporting your hormone health is crucial for overall wellbeing.
When we view hormones through this lens, it becomes clear why simply treating individual symptoms (like sleep aids for insomnia or antidepressants for mood changes) might not address the root cause. Your body is an interconnected system, with hormones playing a vital role in keeping everything running smoothly.
ESTROGEN AND HEALTH: THE ORGANS THAT FEEL THE SHIFT
Source: The G protein-coupled oestrogen receptor GPER in health and disease
The Truth About Hormone Decline in Perimenopause
The journey through perimenopause often starts earlier than most women realize. Jill outlines the typical timeline:
- Mid to late 30s: Progesterone begins declining first
- Early 40s: Erratic fluctuations in estrogen levels begin
- Final years before menopause: Steady estrogen decline
- Throughout this time: Variable testosterone changes
These hormonal changes can trigger a wide range of symptoms:
- Sleep disruption
- Anxiety and mood changes
- Heavier periods
- Brain fog
- Low energy
- Temperature regulation issues
Debunking the Women's Health Initiative Study Myths
One of the biggest barriers to women accessing hormone therapy has been misconceptions from the Women's Health Initiative (WHI) study from the 1990s. Jill explains what really happened:
"The study used synthetic hormones that are not the same as the hormones used in our body. The estrogen was a horse-derived estrogen called Premarin. The progesterone was not a progesterone at all."
Key facts about the WHI study:
- Used synthetic hormones, not bioidentical ones
- Study was prematurely halted in 2002
- Initial breast cancer risk findings were statistically insignificant
- Researchers later retracted their statements
- Women using estrogen actually showed 23% decreased breast cancer risk
When to Start Considering Hormone Therapy
A common myth is that women need to wait until they've gone a full year without periods before starting HRT. Jill strongly disagrees:
"If a doctor says you have to wait until your last period to come in to have hormones, that's outdated advice and a red flag that they may not be a menopause expert."
The ideal time to start exploring hormone therapy options:
- In your 30s: Start researching and finding qualified providers
- During perimenopause: Tracks and address symptoms as they arise
- Within 10 years of menopause: Optimal window for protective benefits
- Even beyond 10 years: Benefits still possible, especially for specific symptoms
Finding the Right Healthcare Provider
Not all healthcare providers are equally qualified to prescribe hormone therapy. Jill recommends:
- Get educated about hormones and HRT basics before appointments
- Ask specifically if they prescribe hormones
- Look for providers who:
Make hormones a key focus of their practice
- Offer multiple treatment options
- Provide ongoing support and monitoring
- Are willing to adjust treatment based on your response
Understanding Different HRT Options
Jill breaks down the main categories of hormone therapy:
Bioidentical Hormones:
- Exactly match hormones made by your body
- Available in FDA-approved formulations
- Can be customized through compounding pharmacies
Synthetic Hormones:
- Modified molecular structure
- Different from natural body hormones
- Often have added ingredients
What to Expect When Starting HRT
Starting hormone therapy is a personalized process. Jill outlines what to expect:
- Initial dosing is rarely the final dose
- Requires monitoring and adjustment
- May experience temporary side effects (the "four B's"):
Bleeding
- Bloating
- Breast tenderness
- "Bitchiness" (emotional reactions)
Most side effects resolve as your body adjusts to the hormones.
Beyond Hormone Therapy: A Holistic Approach to Menopause
While hormone therapy can be transformative, Jill emphasizes the importance of overall lifestyle support:
- Prioritize quality nutrition
- Incorporate strength training
- Focus on stress management
- Maintain social connections
- Get adequate sleep
- Practice mindful eating
Your Next Steps
Whether you choose hormone therapy or not, here's how to move forward:
- Start tracking your symptoms
- Research qualified menopause providers in your area
- Prepare questions for medical consultations
- Consider lifestyle modifications that support hormonal health
- Join supportive communities of other midlife women
Remember, you are the CEO of your body. You deserve accurate information to make informed choices about your health during perimenopause, menopause, and beyond.
About Our Guest: Jill Chmielewski is a Registered Nurse, Women's Health Expert, and Menopause Educator with over 30 years of experience. She serves on the medical advisory board at the Institute of Bioidentical Medicine and created "The Beginner's Guide to Hormone Replacement Therapy." Through her online community Pausing Together, she helps women navigate perimenopause and menopause with confidence.
Connect with Jill Chmielewski: → Website: jillchmielewski.com → Instagram: instagram.com/jill.chmielewski → Community: jillchmielewski.com
About the guest
Jill ChmielewskiRegistered Nurse, Women's Health Expert, and Menopause Educator with over 30 years of experienceGuest on this episode of Pleasure in the Pause.More about them


